The following is a list of notable persons who were born, or who have lived a significant part of their lives, in Erie, Pennsylvania.
Art and Literature
- Richard Anuszkiewicz, founder and foremost artist of Op Art movement
- Moses Billings, early American portrait painter
- Marc Brown, children's book author and illustrator, creator of the Arthur book series
- John Silk Deckard, painter, printmaker, sculptor
- David Greenberger, artist
- Thom Hatch, author and novelist who specializes in the history of the American West, the American Civil War, and the Plains Indian Wars
- Eugene Iverd, illustrator and teacher
- Ron Larson, author of several dozen mathematics textbooks
- Leon Ray Livingston, known as "King of the Hobos"
- Ruth Eleanor Newton, illustrator and designer
- Joseph Plavcan, painter and teacher
- Chuck Rosenthal, author
- Belle Silveira, artist known for her pencil portraits
- Ida M. Tarbell, author, journalist, "muckraker"
- John Totleben, comic book illustrator, known for covers of DC Comics' Swamp Thing
- Michael J. Varhola, author
- Charles Erskine Scott Wood, author and leading civil liberties advocate, best known for "Heavenly Discourse"
Athletics
Business and politics
Film, stage, and television
Military and aerospace
Music
- Art Phillips, guitar, composer, orchestrator, Emmy Award for music score to Santa Barbara www.101.audio
- Alan Baer, tuba, New York Philharmonic
- Harry Burleigh, classical music composer
- Walter Hendl, conductor, composer and pianist
- Peter Mennin, composer and teacher
- Patrick Monahan, lead singer of Train; solo artist; Grammy Award winner
- Chris Vrenna, drummer of rock band Nine Inch Nails
- Jack Stauber, Solo Musician and Songwriter
- War of Ages, Christian metal band
Naturalists
- Joe Root, 19th-century naturalist who lived at Presque Isle State Park
Religion
- Joan Chittister, Benedictine nun, author, and lecturer
- Max C. Currick, Reform rabbi
- Mary Lou Kownacki, Benedictine nun, activist, and writer
- John Mark Gannon, Catholic archbishop
- Theodore Jurewicz, Russian Orthodox priest and Byzantine iconographer
Science, medicine, and academia
- Richard Beals, Yale professor and author of several mathematical textbooks
- David Dausey, professor, author and epidemiologist
- Millicent Goldschmidt, microbiologist, professor emerita at University of Texas
- John Kanzius, inventor; radio and TV engineer and executive
- Tara Keck, professor at University College London, published numerous scholarly articles on neuroplasticity
- Chester L. Sutula, chemist
- Paul Siple, Antarctic explorer who developed the wind chill factor
• Art Phillips, Associate Professor - Universal Business School Sydney Australia, director - lecturer, course advisor, Centre for Entrepreneurship, 2020 ~ 2024
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